PACKED RED CELL DENGAN DELTA Hb DAN JUMLAH ERITROSIT ANEMIA PENYAKIT KRONIS (Packed Red Cells with Delta Hb and Erythrocytes in Anemia of Chronic Disease)

Novita Indayanie, Banundari Rachmawati

Abstract


Anemia chronic disease is the second common cause after iron deficiency anemia with hemoglobin levels below the reference
value. The pathogenesis of anemia should be determined for treatment. Hematinics and or erythropoietin are other treatments besides
transfusion. The transfusion is started when Hb≤7g/dL. The PRC transfusion of 4ml/kg could increase Hb level by 1 g/dL, or 1 unit and
could increase 3–5% of hematocrit. The objective of this study was to know the correlation of PRC unit with delta Hb and erythrocytes
in anemia of chronic disease. The 60 samples examined were from patients of the Kariadi Hospital Semarang suffering from anemia of
chronic disease and who were transfused with PRC from January up to March 2014. The study subjects comprised 28 men (46.7%) and
32 women (53.3%), with a mean age of 47 years. The number of PRC given was between one (1) to four (4) units. The mean delta Hb
was 3.48 and the mean delta erythrocytes was about 1.03 (0.1 to 2.3). There was a significant correlation between PRC units and delta
Hb (r:0.856, p:0.000), as well as delta erythrocytes (r:0.716, p:0.000). Based on this study, it can be concluded that PRC units have a
very strong correlation with delta Hb and as well as with delta erythrocytes in patients suffering from anemia of chronic disease


Keywords


Packed red cells, delta Hb, delta erythrocytes, anemia of chronic disease

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DOI: http://dx.doi.org/10.24293/ijcpml.v21i3.1270

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ACREDITED No. 36a/E/KPT/2016, 23 Mei 2016

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